Russia Scientist Resurrects Frozen Zombie Virus After 48,000 Years

The ability of these " zombie " viruses to infect higher animals, including humans, remains unclear, but researchers warn this suggests viruses "hibernate" under permafrost around the world. is a real threat to humanity.

According to CNN, French professor Jean-Michel Claverie (from the French National Center for Scientific Research CNRS and Aix Marseille University) found these "zombie" virus strains in a frozen state for 48,000 years in class. the soil of an underground, permafrost-covered lake in Russia's frigid Siberian desert, along with several "younger" samples dating back to 27,000 years from a number of other sources, including the carcass of a woolly mammoth twisted.

Professor Claverie and his colleagues brought these "zombie" back to the lab and tried to revive it. Just like a horror movie, these little zombies not only come back to life, but quickly act as if they had never spent tens of thousands of years in the ice tomb.

Amoeba - tiny single-celled organisms - cultured in a laboratory are exposed to the virus and quickly infected by ancient "zombie".

"We see these amoebic viruses as a proxy for all the other viruses that can survive in the permafrost. We see traces of many, many types there. If the virus has infected the amoeba. If they are still alive, there is no reason why other species should not be alive and still able to infect the host," Professor Claverie warned.

The work has just been published in the journal Viruses.

The study adds to the "red alarm" that scientists around the world have been sounding over the years, as the threat of ancient viruses and bacteria revives as human-caused global warming. man caused the permafrost to melt everywhere.

The threat may have come true in 2016, when anthrax bacteria suddenly appeared in Siberia, infecting people and reindeer. It is suspected by the academic community to be an ancient bacteria that has resurrected after 2 million years of hibernation.

Ministers Fume Over Suggested Plan To Ban Smoking In Italy

According to report from local news media, the Italian health minister's suggested plans to extend smoking ban which includes the outdoor areas of parks and bars which drew the wrath of right-wing cabinet colleagues who tagged him a “Communist.”

However, a technocrat with no party affiliation, Minister Orazio Schillaci, said in January that he'd crackdown on smoking, including e-cigarettes, widely used by teenagers.

According to report from La Stampa newspaper on Monday, the new rules will however include the outside areas of bars and at public transport stops. The report further claimed that the prohibition will also be extended to parks if pregnant women and children are present in the area.

Vittorio Sgarbi, Junior Culture Minister, who's known for always expressing his opinions called Schillaci's perspective “intimidating” and thus, said that such bans would instead encourage people to smoke.

Sgarbi told AdnKronos news agency that “this is something typical of an authoritarian and dictatorial communist regime”

According to Italy's top health institute, it recorded about 24% adult Italian smokers in 2022, roughly 12.4 million people and thus, the highest percentage of smokers recorded since 2009.

In 2003, the government passed an indoor smoke ban which came into force two years later.

Fondazione Umberto Veronesi, a health association estimated at least 43,000 death every year which is caused by smoke related reasons in Italy.

But the suggested clampdown also faces skepticism from Deputy Prime Minister and League party leader Matteo Salvini, who quit cigarettes four years ago but said the open-air ban on e-cigarettes was "exaggerated."

"Electronic cigarettes are helping a lot of people to abandon regular cigarettes," he added on Twitter.

First Patient Enrolled in Prospective Randomized Trial with Erectile Dysfunction Using SELUTION SLR

Perfect Selection FIM (PERivic R.Hemostasis debtAlso eagainCTThe ile dysfuction-SELUTION First-In-Man) study will include a total of 54 patients with distal internal pudendal penile artery stenosis and ED. They will be randomized to treatment with either her SELUTION SLR or plain old balloon angioplasty (POBA) and then followed for 12 weeks. The primary efficacy endpoint of this study was angiographic binary restenosis (>50% lumen diameter stenosis) was defined by computed tomography (CT), and the primary safety endpoint was the incidence of major adverse events.

“We are excited to begin this study in such a long-suffering patient population. We hope this study will give these patients a better chance to lead a normal life and we look forward to the results.” increase." tsundu one Professor of Medicine and Director of Cardiology cath lab National Taiwan University Hospital, Over 500 patients with arterogenic erectile dysfunction underwent pudendal and penile artery angioplasty using conventional devices (POBA and/or stents), and restenosis occurred in over 30% of treated patients “We need cutting-edge technology to break through this barrier.

“We are very pleased with the clinical results in many applications of this technology: in-stent restenosis, coronary de novo, both below and above the knee, AV fistula, and now erectile dysfunction. We look forward to the results of this physician-led study as it is an unmet need that impacts the lives of hundreds of millions of people." Jeffrey B. JumpChairman and CEO of MedAlliance.

This study follows a successful feasibility study conducted in Europe of August 2021 including 10 patients with ED.

It is estimated that more than 300 million men worldwide will be affected by ED in 2020, and this number is projected to increase to 322 million by 2025. Nearly 30% of these men were between the ages of 40 and 70. Vascular disease is the most common cause of ED. 70% of the physical causes of ED are due to poor blood circulation to the penis. PDE5 inhibitors (Viagra, Cialis, etc.) are the most commonly used drug treatments for ED, but up to 50% of treated patients experience suboptimal responses.

A potential alternative therapy for these patients is the use of coronary metal stents or balloons to treat the pubic and/or penile arteries via a percutaneous approach. Atherosclerotic obstructive disease of the iliopudendal artery leading to arterial insufficiency into the penis has been reported to affect up to 75% of patients with ED.

SELUTION SLR received CE Mark approval for the treatment of peripheral arterial disease. February 2020 and for the treatment of coronary artery disease May 2020The US FDA has given SELUTION SLR 4 landmark designations. Coronary in-stent restenosis; peripheral below-the-knee and AV-fistula indications.

In August 2021, the first of more than 3,000 patients to be enrolled in a landmark coronary randomized controlled study comparing SELUTION SLR with Limus drug-eluting stents [DES]This is the largest DEB study ever initiated and has the potential to change medical practice.

MedAlliance's DEB technology includes a proprietary MicroReservoir made from a biodegradable polymer blended with the anti-restenotic drug sirolimus. These microreservoirs provide controlled and sustained release of drug for up to 90 days.1The sustained release of sirolimus from stents has proven to be highly effective in both the coronary and peripheral vasculature. Unique to MedAlliance, his CAT™ (Cell Adherent Technology) allows the MicroReservoir to be coated onto the balloon and adhered to the vessel lumen when delivered via an angioplasty balloon.

Media contact:

Richard Kenyon
rkenyon@medalliance.com
+44 7831 569940

About Media Alliance

MedAlliance is a privately held medical technology company. Headquartered in Nyon, Switzerland with office Germany, Singapore UK and united states of america MedAlliance specializes in developing breakthrough technologies and commercializing advanced drug device combination products for the treatment of coronary and peripheral artery disease. For more information, please visit www.medalliance.com.

Obvious drug concentrations in MicroReservoirs and tissues – data archived at MA Med Alliance SA

Poor mental health increases long-term Covid risk, study finds

A study found that people who had symptoms of depression, anxiety, stress and loneliness prior to infection may be at higher risk of developing long-lasting Covid.

Researchers at the Harvard School of Public Health studied more than 54,000 participants from the start of the pandemic and found that high levels of emotional distress before contracting Covid increased the risk of long-term symptoms by 32-46%. discovered.

Over the year of the study, about 3,000 of the participants contracted Covid and were asked about their symptoms and their duration.

Using questions asked about mental health at the start of the study, the team compared responses from those who had long-term Covid and those who did not.

They also found that emotional distress was associated with a 15% to 51% higher risk of long-term COVID-19 impact on daily life.

The increased risk was independent of smoking, asthma, or other health behaviors or conditions, reported in JAMA Psychiatry.

"We were surprised at how strongly pre-Covid-19 mental distress was associated with an increased risk of long-term Covid-19 infection," said study leader Siwen Wang.

"Distress was more strongly associated with prolonged Covid than physical health risk factors such as obesity, asthma, and hypertension.

They noted that other acute respiratory tract infections, such as the flu and the common cold, were associated with more severe mental health conditions and longer duration of symptoms, and previous studies found that distress was associated with post-Lyme disease. chronic symptoms and chronic fatigue. syndrome and fibromyalgia.

However, they stressed that the results should not be misinterpreted as supporting the hypothesis that post-Covid-19 conditions are psychosomatic.

One potential link between psychological distress and long-term Covid could be chronic systemic inflammation and immune dysregulation, they wrote.

Co-author Andrea Roberts said, “In addition to physical health, psychological health should be considered as a long-term COVID-19 risk factor. increasing awareness of mental health, increasing the supply of mental health clinicians, and improving access to care, all increasing the need to provide mental health care to those in need.

According to data from the National Bureau of Statistics, among the elderly between the ages of 35 and 69, women, people living in disadvantaged areas, people working in social care, education, education, health care, and people with other diseases, It has been shown to have the highest self-reported long-term Covid prevalence. A medical condition or disorder that limits another activity.

Last month, NHS England said it would be up to the ICS to decide how to support common practice in dealing with the protracted Covid problem.